一项关于人乳成分对致泻性大肠杆菌在动物模型中肠道黏附影响的综述。
A review of the effect of human milk fractions on the adherence of diarrheogenic Escherichia coli to the gut in an animal model.
作者信息
Ashkenazi S
机构信息
Unit of Pediatric Infectious Diseases, Children's Medical Center of Israel, Beilinson Medical Campus, Petah Tikva.
出版信息
Isr J Med Sci. 1994 May-Jun;30(5-6):335-8.
PMID:8034476
Abstract
We conducted studies showing that nonimmunoglobulin fractions of human milk or colostrum inhibited the adherence of certain diarrheogenic Escherichia coli to the gut. This activity resisted boiling and digestion with trypsin, but was nearly abolished by periodate treatment. The inhibitory activity is therefore related to carbohydrate residues in human milk that probably act as receptor analogues.
摘要
我们开展的研究表明，人乳或初乳的非免疫球蛋白部分可抑制某些致腹泻性大肠杆菌黏附于肠道。这种活性可耐受煮沸和胰蛋白酶消化，但经高碘酸盐处理后几乎丧失。因此，这种抑制活性与人乳中可能作为受体类似物的碳水化合物残基有关。
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