Dusmet M, Merlini M, Chapuis G
Département de chirurgie, Hôpital de la Chaux-de-Fonds.
Helv Chir Acta. 1994 Apr;60(4):489-93.
Hiatus hernia with reflux can be asymptomatic or can lead to severe, complicated esophagitis or even to metaplasia, dysplasia and carcinoma. Ideally all refluxing patients with esophagitis who are not easily and completely controlled with medical therapy should undergo anti-reflux surgery before complications such as ulcers, stricture or columnar metaplasia (Barrett's esophagus) occur. When esophagitis is long-lasting or severe, shortening of the esophagus is common. In such cases the esophagus must be "lengthened" before an anti-reflux procedure can be performed safely. This is the Collis gastroplasty. We have performed 17 Collis-Nissen procedures over 5 years for complicated gastroesophageal reflux disease (GERD). Results were good to excellent in 8 cases, satisfactory in 6 and poor in 3. We conclude that a complete preoperative workup with esophagoscopy (and biopsies), 24-hour pH monitoring and esophageal manometry must be performed in all patients with complicated GERD to allow the best operative procedure to be chosen (gastroplasty-fundoplication, resection or total duodenal diversion). The role of alkaline reflux is also discussed.
伴有反流的食管裂孔疝可能无症状,也可能导致严重的复杂性食管炎,甚至发展为化生、发育异常和癌症。理想情况下,所有患有食管炎且药物治疗难以轻松完全控制反流的患者,应在出现溃疡、狭窄或柱状上皮化生(巴雷特食管)等并发症之前接受抗反流手术。当食管炎持续时间长或病情严重时,食管缩短很常见。在这种情况下,必须先“延长”食管,才能安全地进行抗反流手术。这就是科利斯胃成形术。我们在5年时间里对17例复杂性胃食管反流病(GERD)患者实施了科利斯-尼森手术。结果8例良好至优秀,6例满意,3例不佳。我们得出结论,所有复杂性GERD患者都必须进行全面的术前检查,包括食管镜检查(及活检)、24小时pH监测和食管测压,以便选择最佳的手术方式(胃成形术-胃底折叠术、切除术或全十二指肠转流术)。同时还讨论了碱性反流的作用。