Siegle R J, Wood T
Department of Otolaryngology, Arthur G. James Cancer Hospital and Research Institute, Ohio State University, Columbus 43210.
J Dermatol Surg Oncol. 1994 Jul;20(7):490-3. doi: 10.1111/j.1524-4725.1994.tb03223.x.
Metastatic basal cell carcinoma (MBCC) is rare, with most cases of head and neck origin and from large multi-recurrent tumors. MBCC is very rare from lower extremities and even more rare from primary tumors that were small and treated without local recurrence.
This paper presents a case of MBCC in a 78-year-old woman who had previously undergone resection without local recurrence of a small lower extremity basal cell carcinoma.
MBCC can present atypically with site of origin on lower extremities, initial tumor size small, and nonrecurrence of the primary tumor site. The clinician should be aware of this as well as understand that prompt and aggressive surgical therapy to localized metastases may extend survival.
转移性基底细胞癌（MBCC）较为罕见，大多数病例起源于头颈部且源自大型多次复发肿瘤。下肢来源的MBCC非常罕见，而源自小肿瘤且治疗后无局部复发的原发性肿瘤的MBCC则更为罕见。
本文报告一例78岁女性的MBCC病例，该患者此前接受了下肢小基底细胞癌切除术且无局部复发。
MBCC可能表现不典型，起源于下肢，初始肿瘤较小，且原发肿瘤部位无复发。临床医生应了解这一点，并明白对局限性转移灶进行及时、积极的手术治疗可能延长生存期。
