Benson-Mitchell R, Tolley N, Croft C B, Roberts D
Royal National Throat, Nose and Ear Hospital, London.
J Laryngol Otol. 1994 May;108(5):431-2. doi: 10.1017/s0022215100126994.
Wegener's granuloma is a systemic necrotizing vasculitis which predominantly affects the upper and lower respiratory tracts and kidneys. The nose and paranasal sinuses are often the first or main sites to be affected. Equally ear involvement is common and a recognized early manifestation of the disease. Salivary gland involvement is rare and is usually part of more widespread systemic involvement. We present a 34-year-old female with a six-week history of hearing loss and a unilateral parotid swelling. One year previously she was diagnosed as having myalgic encephalomyelitis following a long period of post-viral malaise. The case points to the difficulties encountered when Wegener's granuloma presents in an unusual and varied way. A high index of suspicion coupled with early diagnosis and treatment is essential. The patient made a good recovery.
韦格纳肉芽肿是一种全身性坏死性血管炎，主要累及上、下呼吸道和肾脏。鼻和鼻窦常是最先或主要受累部位。耳部受累同样常见，是该疾病公认的早期表现。唾液腺受累罕见，通常是更广泛全身受累的一部分。我们报告一名34岁女性，有六周听力丧失和单侧腮腺肿大病史。一年前，她在经历长时间病毒感染后不适后被诊断为患有肌痛性脑脊髓炎。该病例指出了韦格纳肉芽肿以不寻常和多样方式表现时所遇到的困难。高度怀疑加上早期诊断和治疗至关重要。患者恢复良好。
