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经皮腔内冠状动脉成形术失败后行“挽救性”定向冠状动脉斑块旋切术。

"Rescue" directional coronary atherectomy after unsuccessful percutaneous transluminal coronary angioplasty.

作者信息

Harris W O, Berger P B, Holmes D R, Garratt K N, Bresnahan J F, Bell M R

机构信息

Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester, Minnesota 55905.

出版信息

Mayo Clin Proc. 1994 Aug;69(8):717-22. doi: 10.1016/s0025-6196(12)61087-8.

Abstract

OBJECTIVE

To evaluate the outcome in patients who underwent directional coronary atherectomy after unsuccessful balloon angioplasty.

DESIGN

We conducted a retrospective computerized data bank search of patients in whom unsuccessful balloon angioplasty and subsequent "rescue" coronary atherectomy had been performed at the Mayo Clinic between Nov. 1, 1988, and May 1, 1993.

MATERIAL AND METHODS

Among the 336 patients who underwent directional coronary atherectomy during the study period, in 16 the procedure was a rescue attempt. The mean age of these 16 study patients was 67 years. The following vessels were treated: left anterior descending coronary artery, six patients; right coronary artery, six; circumflex artery, two; and saphenous vein graft, two. Coronary angioplasty had failed because of dissection in eight patients, elastic recoil without evident dissection in seven, and recurrent thrombus without evident dissection in one.

RESULTS

After coronary atherectomy, the mean stenosis was 41% (in comparison with 90% before coronary angioplasty and 71% after coronary angioplasty). Both angiographic success (20% or more decrease in stenosis after tissue removal and a final stenosis of less than 50%) and clinical success (angiographic success without in-hospital Q-wave myocardial infarction, bypass operation, or death) were achieved in 10 patients. Adventitia was obtained in two patients, both of whom underwent atherectomy for elastic recoil. In six patients, a stenosis of more than 50% remained after atherectomy; one patient suffered a Q-wave myocardial infarction, and one underwent emergent coronary artery bypass grafting. No deaths occurred in the study group. During follow-up (mean, 22 +/- 19 months), one patient suffered a non-Q-wave myocardial infarction, and two others underwent elective coronary artery bypass grafting. Eleven patients were asymptomatic at last contact. Repeated angiography, done in five patients a mean of 3.4 +/- 3.1 months after the procedure, showed restenosis in three.

CONCLUSION

Rescue directional coronary atherectomy seems to be safe and effective in achieving angiographic and clinical successes in carefully selected patients after unsuccessful coronary angioplasty.

摘要

目的

评估球囊血管成形术失败后接受定向冠状动脉斑块旋切术患者的治疗结果。

设计

我们对1988年11月1日至1993年5月1日期间在梅奥诊所接受球囊血管成形术失败并随后进行“挽救性”冠状动脉斑块旋切术的患者进行了回顾性计算机数据库检索。

材料与方法

在研究期间接受定向冠状动脉斑块旋切术的336例患者中,16例进行了挽救性尝试。这16例研究患者的平均年龄为67岁。治疗的血管如下:左前降支冠状动脉,6例;右冠状动脉,6例;回旋支动脉,2例;大隐静脉桥血管,2例。冠状动脉血管成形术失败的原因:8例为夹层形成,7例为无明显夹层的弹性回缩,1例为无明显夹层的复发性血栓形成。

结果

冠状动脉斑块旋切术后,平均狭窄率为41%(冠状动脉血管成形术前为90%,冠状动脉血管成形术后为71%)。10例患者实现了血管造影成功(组织切除后狭窄减少20%或更多且最终狭窄小于50%)和临床成功(血管造影成功且无院内Q波心肌梗死、搭桥手术或死亡)。2例患者获取了外膜,这2例均因弹性回缩接受了斑块旋切术。6例患者在斑块旋切术后狭窄率仍超过50%;1例患者发生Q波心肌梗死,1例接受了急诊冠状动脉搭桥术。研究组无死亡病例。在随访期间(平均22±19个月),1例患者发生非Q波心肌梗死,另外2例接受了择期冠状动脉搭桥术。最后一次随访时11例患者无症状。5例患者在术后平均3.4±3.1个月进行了重复血管造影,其中3例显示有再狭窄。

结论

对于冠状动脉血管成形术失败后经过精心挑选的患者,挽救性定向冠状动脉斑块旋切术在实现血管造影成功和临床成功方面似乎是安全有效的。

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