Dellon A L, Dellon E S, Seiler W A
Division of Plastic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Microsurgery. 1994;15(4):265-8. doi: 10.1002/micr.1920150409.
The streptozotocin-induced diabetic rat has changes in the hind-foot walking track pattern that are progressive over time. The present study investigated the effect of microsurgical neurolysis of the posterior tibial nerve and its branches in the tarsal tunnel on this pattern. The tarsal tunnel decompression was done at the time of onset of diabetes. The results of the study confirmed the progressive pattern of track abnormalities in this rat model, P < .05. The results demonstrated that rats in which the tarsal tunnel had been decompressed at the onset of their diabetes did not develop the characteristically abnormal diabetic walking track pattern. Rather, the track patterns of the decompressed tarsal tunnel diabetic rats were not significally different from a nondiabetic control population.
链脲佐菌素诱导的糖尿病大鼠后足行走轨迹模式会随时间逐渐发生变化。本研究调查了跗管内胫后神经及其分支的显微外科神经松解术对此模式的影响。在糖尿病发病时进行跗管减压术。研究结果证实了该大鼠模型中轨迹异常的渐进模式，P < 0.05。结果表明，在糖尿病发病时进行跗管减压的大鼠并未出现典型的异常糖尿病行走轨迹模式。相反，减压跗管糖尿病大鼠的轨迹模式与非糖尿病对照组并无显著差异。
