Mertelli M F, Rambotti P, Velardi A, Aversa F
Folia Haematol Int Mag Klin Morphol Blutforsch. 1978;105(3):306-11.
A 78-year old man is presented with a characteristic case history and physical and laboratory findings typical of angio-immunoblastic lymphadenopathy with dysproteinemia (AILD). The disease had an acute onset with constitutional symptoms, generalized lymphadenopathy and hepato-splenomegaly. The presence of a large pleural effusion was of particular interest. Histologically the distinctive feature was a pronounced proliferation of small blood vessels and immunoblasts in the lymph nodes. Management of patient with AILD is problematic. Since AILD is a non-neoplastic process, symptomatic treatment with small doses of steroids, if necessary, would seem to be the best therapeutic approach. However, in our patient, as well as in other cases reported in the literature, a rapid and long standing (18 months so far in our case) complete remission was obtained with a short cycle of chemiotherapy.
一名78岁男性患者具有血管免疫母细胞性淋巴结病伴蛋白异常血症（AILD）的典型病史、体格检查及实验室检查结果。该病急性起病，伴有全身症状、全身淋巴结肿大及肝脾肿大。大量胸腔积液的存在尤为引人关注。组织学上，其显著特征是淋巴结内小血管和免疫母细胞明显增生。AILD患者的治疗存在问题。由于AILD是一种非肿瘤性病变，必要时小剂量使用类固醇进行对症治疗似乎是最佳治疗方法。然而，在我们的患者以及文献报道的其他病例中，短疗程化疗获得了快速且持久（我们的病例至今已持续18个月）的完全缓解。
