Kostina Z I, Pokhodzeĭ I V, Raznatovskiĭ I M, Mikheev G N, Vlasova M M, Khorovskaia L A, Alekseev D Iu
Probl Tuberk. 1994(2):32-5.
A total of 132 patients with generalized sarcoidosis (GS) who amounted to 2.8% out of 4700 examinees and followed-up patients with respiratory sarcoidosis were studied. The pathomorphological study of biopsy specimens, X-ray functional, and immunological studies are of great importance in the diagnosis of GS. The latter in the examinees was characterized by the most common lesions to the skin, subcutaneous fat, peripheral lymph nodes, liver, spleen, central and peripheral nervous systems and eyes. The combined pathogenetic therapy developed, which involves corticosteroidal hormones and anabolic drugs, immunomodulators, antioxidants and antihypoxants has been shown to be effective in 62% of the patients.
对4700名受检者和呼吸性结节病随访患者中总计132例全身性结节病(GS)患者进行了研究,这些患者占受检者总数的2.8%。活检标本的病理形态学研究、X线功能研究和免疫学研究对GS的诊断具有重要意义。后者在受检者中的特征是皮肤、皮下脂肪、外周淋巴结、肝脏、脾脏、中枢和外周神经系统以及眼睛出现最常见的病变。已研发出的联合致病疗法,包括皮质类固醇激素、合成代谢药物、免疫调节剂、抗氧化剂和抗缺氧剂,已证明对62%的患者有效。