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[肺结节病和肺结核患者的诊断与治疗特点]

[Specific features of diagnosis and treatment of patients with pulmonary sarcoidosis and tuberculosis].

作者信息

Kostina Z I, Brazhenko N A, Gerasimova E V, Kol'nikova O V

出版信息

Probl Tuberk. 1998(2):10-3.

PMID:9613175
Abstract

In the past 30 years, the authors examined and treated 6473 patients with pulmonary sarcoidosis, of them 105 (1.6%) had contacted with the individuals isolating Mycobacterium tuberculosis and 45 (0.7%) had a history of various forms of pulmonary tuberculosis; however, the patients with pulmonary sarcoidosis had neither exacerbations nor relapses. Of the 6473 patients, 41 (0.63%) was diagnosed as having active pulmonary tuberculosis, including 20 with focal pulmonary tuberculosis, 13 with disseminated pulmonary tuberculosis, 4 pulmonary tuberculosis with infiltrative, and other 4 with destructive pulmonary tuberculosis, disseminated and destructive pulmonary tuberculosis occurred in the progressive pulmonary sarcoidosis. The etiopathogenetic treatment of tuberculosis with at least 3-4 drugs (small-dose hormones, antioxidants, immunomodulators) was found to cure the two abnormalities in 95.2% and in 4.8% of cases, the pathological process became chronic when limited disseminated pulmonary tuberculosis was concurrent with disseminated pulmonary sarcoidosis.

摘要

在过去30年里,作者检查并治疗了6473例肺结节病患者,其中105例(1.6%)曾与隔离的结核分枝杆菌感染者接触,45例(0.7%)有各种形式的肺结核病史;然而,这些肺结节病患者既没有病情加重也没有复发。在这6473例患者中,41例(0.63%)被诊断为活动性肺结核,其中20例为局灶性肺结核,13例为播散性肺结核,4例为浸润性肺结核,另外4例为毁损性肺结核,播散性和毁损性肺结核发生于进行性肺结节病中。发现采用至少3 - 4种药物(小剂量激素、抗氧化剂、免疫调节剂)对结核病进行病因治疗,在95.2%的病例中可治愈这两种异常情况,在4.8%的病例中,当局限性播散性肺结核与播散性肺结节病同时存在时,病理过程会变为慢性。

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