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[聚山梨醇酯作为用于中耳炎局部治疗药物的固定化基质]

[Polysorb as an immobilizing matrix for the drugs used for the local therapy of otitis media].

作者信息

Enin E P, Morenko V M

出版信息

Vestn Otorinolaringol. 1993 Jul-Aug(4):41-2.

PMID:8036759
Abstract

Local treatment of inflammation by continuous introduction of the drug on the sorbent matrix is supposed to be an ideal method as it warrants prolonged supply with the drug administered in a single dose. Such treatment was given to 77 patients suffering from acute and chronic otitis media. The follow-up results show the sorbent to reduce the tissue inflammation and exudation within the initial 5-10 hours. Perforation closes much more promptly than in other treatments for acute and recurrent otitis media.

摘要

通过在吸附剂基质上持续引入药物来对炎症进行局部治疗被认为是一种理想的方法,因为它能保证单次给药后药物的持续供应。对77例急慢性中耳炎患者进行了这种治疗。随访结果显示,吸附剂在最初的5 - 10小时内可减轻组织炎症和渗出。与急性和复发性中耳炎的其他治疗方法相比,穿孔闭合得更快。

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