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俄勒冈州高血压与肾脏疾病的分布情况

Distribution of hypertension and renal disease in Oregon.

作者信息

Morton W E, Knudsen J C, Porter G A

出版信息

Public Health Rep. 1975 Jan-Feb;90(1):34-43.

Abstract

Expecting to find agreement between the geographic distribution of hypertension and renal disease, we developed regional mortality rates for 1950-72 and prevalence rates for a Selective Service cohort born in 1939-41 and examined during 1957-69. For this purpose the State's counties were grouped into eight geographically homogeneous regions. The general decline in hypertension mortality was most pronounced in Portland, Oregon's major urban center. However, the decline halted during 1968-72 in the southern Cascade region which has become an area of relatively higher risk within the State. During these 23 years nephritis mortality fell, kidney infection mortality was stable, and both syndromes showed peak mortality in other, different regions of the State. The geographic pattern of hypertension prevalence among the draftee cohort resembled the 1963-67 hypertension mortality pattern, but more recent morbidity data are needed to confirm the southern Cascade region's recent change to a high-risk area. Of 529 draftees with diagnosed hypertension, only 35 percent of the cases were previously known, only 7 percent has had any previous treatment, and only 7 percent were associated with known renal conditions. Among 521 registrants with a history of renal disorders, the prevalence of hypertension was increased for all categories of renal disease but was significantly high only for those with a history of glomerulonephritis. To date in Oregon we have found no evidence that renal disorders are major determinants of hypertension morbidity or mortality.

摘要

为了探寻高血压与肾脏疾病的地理分布之间是否存在一致性,我们编制了1950年至1972年的区域死亡率以及一个出生于1939年至1941年且在1957年至1969年期间接受检查的选征兵队列的患病率。为此,该州的各县被划分为八个地理上同质的区域。高血压死亡率的总体下降在俄勒冈州的主要城市中心波特兰最为显著。然而,在喀斯喀特山脉南部地区,这种下降在1968年至1972年期间停止了,该地区已成为该州内风险相对较高的区域。在这23年中,肾炎死亡率下降,肾脏感染死亡率稳定,并且这两种病症在该州其他不同区域呈现出死亡率峰值。选征兵队列中高血压患病率的地理模式类似于1963年至1967年的高血压死亡率模式,但需要更新的发病率数据来证实喀斯喀特山脉南部地区近期转变为高风险区域这一情况。在529名被诊断患有高血压的选征兵中,只有35%的病例之前已知,只有7%曾接受过任何治疗,并且只有7%与已知的肾脏疾病有关。在521名有肾脏疾病史的登记人员中,各类肾脏疾病的高血压患病率均有所上升,但仅在有肾小球肾炎病史的人群中显著升高。到目前为止,在俄勒冈州,我们尚未发现证据表明肾脏疾病是高血压发病率或死亡率的主要决定因素。

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