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使用带有可适配立体定位装置的常规乳腺摄影台对乳腺病变进行立体定位针芯活检。

Stereotaxic needle core biopsy of breast lesions using a regular mammographic table with an adaptable stereotaxic device.

作者信息

Caines J S, McPhee M D, Konok G P, Wright B A

机构信息

Department of Diagnostic Imaging, Camp Hill Medical Center, Halifax, N.S., Canada.

出版信息

AJR Am J Roentgenol. 1994 Aug;163(2):317-21. doi: 10.2214/ajr.163.2.8037022.

Abstract

OBJECTIVE

Fine-needle aspiration and stereotaxic needle core biopsy (SNCB) are techniques used in the workup of breast lesions suggestive of cancer. Many surgeons are reluctant to rely on fine needle results, and until now, SNCB could be done only with a dedicated biopsy table. Our study was done to determine whether SNCB could be performed safely and effectively with a regular mammography unit and an added stereotaxic device.

SUBJECTS AND METHODS

SNCB was performed on 254 patients by using a Siemens Mammomat 2 regular mammography table with an added stereotaxic device. Patients were referred from a breast screening center, a local tertiary care center, and from our own center. Patients who had unequivocal histopathologic evidence of a benign process (133 of 254 patients) did not undergo surgical biopsy and are being followed up mammographically. The remainder (121 patients) all had surgical biopsies.

RESULTS

Sufficient material for histologic analysis was obtained in 249 (98%) of 254 cases. In 31 of 254 cases, sampling was problematic. This group comprised cases in which the patient moved within the compression device, the mammographic and histologic diagnoses were discordant, or calcifications were not present in the core sample when the indication for SNCB was the presence of microcalcifications. This group all had open biopsies. In 25 of 254 cases, the pathologic findings were suggestive of cancer. Cancer was detected in 11 of these cases on open biopsy. Of the 14 benign cases, 11 showed atypical features or ductal hyperplasia on open biopsy. Malignant tumor was diagnosed in 60 of 254 cases by SNCB. Corresponding malignant tumor was seen in 59 of 60 of the open biopsy specimens.

CONCLUSION

The SNCB technique is not limited to use on a dedicated biopsy table but can be readily adapted to a regular mammography unit. It is a safe, reliable and cost-effective procedure that often spares the patient a surgical procedure.

摘要

目的

细针穿刺抽吸活检和立体定向针芯活检(SNCB)是用于检查疑似乳腺癌的乳腺病变的技术。许多外科医生不愿依赖细针穿刺结果,而且直到现在,SNCB只能在专用活检台上进行。我们开展这项研究是为了确定使用常规乳腺摄影设备和附加的立体定向装置能否安全有效地进行SNCB。

对象与方法

使用配备了附加立体定向装置的西门子Mammomat 2常规乳腺摄影台对254例患者进行SNCB。患者来自乳腺筛查中心、当地三级护理中心以及我们自己的中心。有明确良性病变组织病理学证据的患者(254例患者中的133例)未接受手术活检,而是接受乳腺摄影随访。其余患者(121例)均接受了手术活检。

结果

254例病例中有249例(98%)获得了足够用于组织学分析的材料。254例病例中有31例采样存在问题。该组包括患者在压迫装置内移动、乳腺摄影和组织学诊断不一致,或者当SNCB的指征是存在微钙化时,针芯样本中未发现钙化的病例。该组患者均接受了开放活检。254例病例中有25例的病理结果提示为癌症。其中11例在开放活检时检测到癌症。在14例良性病例中,11例在开放活检时显示非典型特征或导管增生。SNCB在254例病例中诊断出60例恶性肿瘤。在60例开放活检标本中的59例中发现了相应的恶性肿瘤。

结论

SNCB技术并不局限于在专用活检台上使用,而是可以很容易地应用于常规乳腺摄影设备。这是一种安全、可靠且具有成本效益的方法,通常可使患者免于手术。

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