Blevins F T, Hecker A T, Bigler G T, Boland A L, Hayes W C
Orthopaedic Biomechanics Laboratory, Charles A. Dana Research Institute, Beth Israel Hospital, Boston, Massachusetts 02215.
Am J Sports Med. 1994 May-Jun;22(3):328-33. doi: 10.1177/036354659402200306.
Over 50% of all knee injuries involve partial or complete tear of the anterior cruciate ligament. Surgical reconstruction of this ligament using an isometrically placed bone-patellar tendon-bone autograft is the current technique of choice; however, harvest of patellar tendon as a free graft can lead to increased morbidity. To address this issue, allogenic patellar tendon grafts have been introduced as alternatives to autogenic graft material. The purpose of this study was to examine effects of age and strain rate on tensile strength, modulus, and failure mode of bone-patellar tendon-bone allografts from a typical population of tissue donors. Eighty-two, fresh-frozen, bone-patellar tendon-bone allografts were harvested from 25 different donors, aged 17 to 54. Paired grafts from individual patellar tendons were assigned randomly to tensile testing at either 10% or 100% elongation per second. Tensile strength, modulus, and failure mode were not significantly different for tests conducted at these 2 strain rates. Correlations between tensile strength and age were not significant for tests conducted at either strain rate. Specimens tested at a strain rate of 100% per second exhibited weak but significant negative correlation between modulus and age, with modulus decreasing 25% over the age range examined.
超过50%的膝关节损伤涉及前交叉韧带部分或完全撕裂。目前，使用等距放置的骨-髌腱-骨自体移植物对该韧带进行手术重建是首选技术；然而，取髌腱作为游离移植物会导致发病率增加。为了解决这个问题，同种异体髌腱移植物已被引入作为自体移植物材料的替代物。本研究的目的是研究年龄和应变率对来自典型组织供体人群的骨-髌腱-骨同种异体移植物的拉伸强度、模量和失效模式的影响。从25名年龄在17至54岁的不同供体中获取了82个新鲜冷冻的骨-髌腱-骨同种异体移植物。来自单个髌腱的配对移植物被随机分配以每秒10%或100%的伸长率进行拉伸测试。在这两种应变率下进行的测试中，拉伸强度、模量和失效模式没有显著差异。在任何一种应变率下进行的测试中，拉伸强度与年龄之间的相关性均不显著。以每秒100%的应变率测试的标本在模量与年龄之间表现出微弱但显著的负相关，在所研究的年龄范围内模量下降了25%。
