Circulatory failure in septic shock. Nitric oxide: too much of a good thing?
作者信息
Brady A J, Poole-Wilson P A
机构信息
Department of Cardiac Medicine, National Heart and Lung Institute, London.
出版信息
Br Heart J. 1993 Aug;70(2):103-5. doi: 10.1136/hrt.70.2.103.
Abstract
摘要
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Polymerized hemoglobin restores cardiovascular and kidney function in endotoxin-induced shock in the rat.聚合血红蛋白可恢复大鼠内毒素诱导性休克中的心血管和肾脏功能。
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本文引用的文献
1
Profound but reversible myocardial depression in patients with septic shock.脓毒性休克患者存在严重但可逆的心肌抑制。
Ann Intern Med. 1984 Apr;100(4):483-90. doi: 10.7326/0003-4819-100-4-483.
2
The effects of high-dose corticosteroids in patients with septic shock. A prospective, controlled study.大剂量皮质类固醇对感染性休克患者的影响。一项前瞻性对照研究。
N Engl J Med. 1984 Nov 1;311(18):1137-43. doi: 10.1056/NEJM198411013111801.
3
Patterns of septic shock in man--a detailed study of 56 patients.人类脓毒性休克模式——对56例患者的详细研究
Ann Surg. 1967 Oct;166(4):543-62. doi: 10.1097/00000658-196710000-00004.
4
Left ventricular performance in septic shock: reversible segmental and global abnormalities.感染性休克时的左心室功能：可逆性节段性和整体异常。
Am Heart J. 1985 Aug;110(2):402-9. doi: 10.1016/0002-8703(85)90163-2.
5
A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock.大剂量甲泼尼龙治疗严重脓毒症和脓毒性休克的对照临床试验。
N Engl J Med. 1987 Sep 10;317(11):653-8. doi: 10.1056/NEJM198709103171101.
6
NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?NG-甲基精氨酸是一种内皮源性一氧化氮合成抑制剂，在豚鼠中是一种强效升压剂：一氧化氮在体内调节血压吗？
Biochem Biophys Res Commun. 1989 Apr 28;160(2):881-6. doi: 10.1016/0006-291x(89)92517-5.
7
The cardiovascular response of normal humans to the administration of endotoxin.正常人类对内毒素给药的心血管反应。
N Engl J Med. 1989 Aug 3;321(5):280-7. doi: 10.1056/NEJM198908033210503.
8
Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man.内皮源性一氧化氮对人体外周小动脉张力的影响。
Lancet. 1989 Oct 28;2(8670):997-1000. doi: 10.1016/s0140-6736(89)91013-1.
9
Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis.
Biochem Biophys Res Commun. 1990 Nov 15;172(3):1132-8. doi: 10.1016/0006-291x(90)91565-a.
10
Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy.人类脓毒症休克。对发病机制、心血管功能障碍及治疗认识的进展。
Ann Intern Med. 1990 Aug 1;113(3):227-42. doi: 10.7326/0003-4819-113-3-227.
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