Lee E J, Kim K R, Lim S K, Lee H C, Kim D I, Kim S H, Huh K B
Department of Internal Medicine, Yong Dong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Eur J Endocrinol. 1994 Jul;131(1):109-12. doi: 10.1530/eje.0.1310109.
We present a 55-year-old female with a thyrotropin (TSH)-secreting pituitary adenoma who had been treated with somatostatin analog octreotide acetate (SMS 201-995) for 4 months. Subcutaneous injection of 100 micrograms octreotide acetate twice daily resulted in significant reduction of the TSH, thyroid hormone, and tumor size. During the treatment, there was no evidence of any side effects. We may conclude that octreotide acetate administration is an effective treatment in patients with TSH-secreting pituitary adenoma for suppressing TSH hypersecretion and reducing the size of the tumor.
我们报告一例55岁分泌促甲状腺激素（TSH）的垂体腺瘤女性患者，该患者已接受生长抑素类似物醋酸奥曲肽（SMS 201-995）治疗4个月。每日两次皮下注射100微克醋酸奥曲肽可使TSH、甲状腺激素水平及肿瘤大小显著降低。治疗期间，未发现任何副作用。我们可以得出结论，对于分泌TSH的垂体腺瘤患者，给予醋酸奥曲肽是一种有效治疗方法，可抑制TSH分泌过多并减小肿瘤大小。
