Cuzick J, Mossman J, Stewart H
Imperial Cancer Research Fund, London, U.K.
Cancer. 1994 Aug 1;74(3 Suppl):1160-3. doi: 10.1002/1097-0142(19940801)74:3+<1160::aid-cncr2820741527>3.0.co;2-z.
The activities of the United Kingdom Co-ordinating Committee on Cancer Research in the area of breast cancer trials were reviewed. Current trials concern the management of ductal carcinoma in situ, the length of time tamoxifen should be given in the adjuvant setting, and trials of the use of chemotherapy. A trial of the use of tamoxifen to prevent breast cancer is being piloted in anticipation of a national study, and trials of the interval and age at which to undertake mammographic screening are also underway.
对英国癌症研究协调委员会在乳腺癌试验领域的活动进行了审查。当前的试验涉及原位导管癌的管理、辅助治疗中他莫昔芬的给药时长以及化疗应用的试验。一项关于使用他莫昔芬预防乳腺癌的试验正在进行试点,以期开展一项全国性研究,同时关于进行乳房X光筛查的间隔时间和年龄的试验也在进行中。