Müller N, Klages U, Günther W
Psychiatric Hospital, University of Munich, Germany.
Gen Hosp Psychiatry. 1994 Mar;16(2):138-40. doi: 10.1016/0163-8343(94)90059-0.
The case of a woman who suffered from hepatic encephalopathy is described. The psychiatric symptoms presented first as a delirium, changing into a manic syndrome. As the neurotoxic direct fraction of bilirubin was greater than 100 times normal, increasing and decreasing in a parallel fashion with the psychiatric symptoms, direct bilirubin is assumed to play a role in the pathogenesis of this case. This is discussed in the context of bilirubin encephalopathy, very seldom diagnosed in adults.
本文描述了一名患有肝性脑病的女性病例。其精神症状最初表现为谵妄，随后转变为躁狂综合征。由于胆红素的神经毒性直接组分比正常水平高100倍以上，且与精神症状呈平行增减，因此推测直接胆红素在该病例的发病机制中起作用。本文将在胆红素脑病的背景下对此进行讨论，胆红素脑病在成人中很少被诊断出来。
