Batra Y K, Sarnaik R M, Gupta S, Jindal S K
Department of Anaesthesiology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Indian J Chest Dis Allied Sci. 1993 Oct-Dec;35(4):179-83.
During the last 4 years, fifty-seven patients of acute severe asthma (ASA) were admitted to intensive care unit (ICU). Twenty-three patients required mechanical ventilation (MV) on 25 occasions. Indications to intubate were persistent hypoxia (PaO2 < or = 55 mm Hg) or hypercapnia with respiratory acidosis (64%), abnormal mentation (24%) and respiratory arrest (12%). All the patients were monitored for clinical features, arterial blood gases (ABG) and peak airway pressure (PAP). During MV, there was one case of pneumothorax (4%), seven (28%) cases of transient hypertension and one (4%) patient died. Mean duration of MV was 3 days and the outcome was favourable. Therefore, resorting to aggressive treatment early in the course of disease proves life saving in acute severe asthma.
在过去4年中，57例急性重症哮喘（ASA）患者被收入重症监护病房（ICU）。23例患者有25次需要机械通气（MV）。插管指征为持续性低氧血症（动脉血氧分压≤55 mmHg）或伴有呼吸性酸中毒的高碳酸血症（64%）、意识异常（24%）和呼吸骤停（12%）。所有患者均监测临床特征、动脉血气（ABG）和气道峰压（PAP）。在机械通气期间，有1例发生气胸（4%），7例（28%）出现短暂性高血压，1例（4%）患者死亡。机械通气的平均持续时间为3天，结果良好。因此，在疾病早期采取积极治疗在急性重症哮喘中被证明可挽救生命。
