Quiñones Mateu M E, Finol H J, Sucre L E, Torres S H
Center of Electron Microscopy, Faculty of Science, Central University of Venezuela, Los Chaguaramos, Caracas.
J Comp Pathol. 1994 Jan;110(1):79-89. doi: 10.1016/s0021-9975(08)80272-1.
Skeletal muscle biopsy specimens were taken from 10 male horses naturally infected with Trypanosoma evansi and from 10 uninfected males. An indirect fluorescent antibody test was used to provide a rapid and reliable indication of infection. Histological, histochemical and transmission electron microscopical techniques were used to examine skeletal muscle. The ultrastructural features in muscle fibres were those usually seen in autoimmune disease, namely fibre and capillary necrosis and mononuclear cell infiltration, consisting of macrophages. Changes in fibre-type percentages did not occur in response to the parasite, but alterations in fibre size and capillary supply were found in the parasitized horses.
从10匹自然感染伊氏锥虫的雄性马和10匹未感染的雄性马身上采集骨骼肌活检标本。采用间接荧光抗体试验以快速可靠地指示感染情况。运用组织学、组织化学和透射电子显微镜技术检查骨骼肌。肌纤维中的超微结构特征是自身免疫性疾病中常见的特征，即纤维和毛细血管坏死以及由巨噬细胞组成的单核细胞浸润。纤维类型百分比并未因寄生虫而发生变化，但在感染寄生虫的马匹中发现了纤维大小和毛细血管供应的改变。
