果蝇中两种致死突变的频率与X射线剂量之间的关系
On the relationship between the frequency of two types of lethal-mutation and x-ray doses in Drosophila.
作者信息
Matsudaira Y, Yamasaki T
出版信息
Mutat Res. 1975 Mar;27(3):341-6. doi: 10.1016/0027-5107(75)90291-2.
The dose-frequency relationship for each of 2 types of lethal mutations, fractional- and whole-lethal, was obtained using X-rays on Drosophila melanogaster. The results show that fractional-lethal mutations are induced by X-rays, and also that the proportion of fractional-lethal mutations in the total of mutations tends to decrease with increasing doses, namely, 61% at o R, 47% at 500 R, 37% at 1000 R and 20% at 2000 R. The same tendency is observed with visible mutations. In order to consider the problems related to the above results, the relationship between the true frequency and the observed frequency of the induced lethal mutations is discussed, taking into consideration the existence of the ostensible whole-lethal and the ostensible normal.
利用X射线对黑腹果蝇进行照射，得出了两种致死突变类型（部分致死和完全致死）各自的剂量-频率关系。结果表明，X射线可诱导部分致死突变，而且在总突变中部分致死突变的比例往往会随着剂量增加而降低，即：在0伦琴时为61%，500伦琴时为47%，1000伦琴时为37%，2000伦琴时为20%。在可见突变中也观察到了同样的趋势。为了探讨与上述结果相关的问题，考虑到表面完全致死和表面正常情况的存在，对诱导致死突变的真实频率与观察频率之间的关系进行了讨论。
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