对麻醉品成瘾患者进行直接抗球蛋白试验。

Direct antiglobulin tests in narcotic addicted patients.

作者信息

Cushman P, Maniatis A

出版信息

Transfusion. 1975 Mar-Apr;15(2):107-10. doi: 10.1046/j.1537-2995.1975.15275122802.x.

DOI:10.1046/j.1537-2995.1975.15275122802.x

Abstract

Direct Antiglobulin Tests (DAT) as well as a number of immunological parameters (immunoglobulin levels, latex fixation, VDRL) were studied in 168 narcotic-addicted patients. Of these, 94 were untreated narcotic addicts (Group I), 61 were methadone maintained patients (Group II), and 13 had completed successful detoxification with methadone and were drug-free (Group III). Weakly positive DAT were detected in 2.1 per cent of individuals in Group I, 18 per cent in Group II, and 15 per cent in Group III. The reactions were usually transient. A number of other immunological aberrations were also present in individuals of all three groups, but there was no correlation between these parameters and the positive direct antiglobulin reactions.

摘要

对168名吸毒成瘾患者进行了直接抗球蛋白试验（DAT）以及一些免疫学参数（免疫球蛋白水平、乳胶凝集试验、性病研究实验室试验）的研究。其中，94名是未经治疗的吸毒成瘾者（第一组），61名是接受美沙酮维持治疗的患者（第二组），13名已成功完成美沙酮脱毒且无毒品依赖（第三组）。第一组中2.1%的个体、第二组中18%的个体以及第三组中15%的个体检测到DAT弱阳性。这些反应通常是短暂的。所有三组个体中还存在许多其他免疫异常情况，但这些参数与直接抗球蛋白阳性反应之间没有相关性。