[钙对锶中毒病程的影响]

[Effects of calcium on the course of strontium toxicosis].

作者信息

Babarykin D A, Valinietse M Iu, Bauman V K, Reĭsner N A

出版信息

Vopr Pitan. 1993 Mar-Apr(2):32-5.

Abstract

Chronic intake of Sr for 20 days by chickens caused in them a delay in body mass increase and symptoms of rickets in spite of complete provision with vitamin D. There were low levels of Ca, P, enhanced activity of alkaline phosphatase in the serum, inhibited mineralization of bone tissue, reduced levels of vitamin D-dependent calcium-binding protein, Sr accumulation in various tissues. Enrichment with Ca of the chickens ration diminished the above signs of Sr toxicosis. It is suggested that a protective effect of Ca in chronic Sr toxicity may be due to more active discrimination of Sr against Ca in intestinal assimilation of these cations.

摘要

鸡长期摄入锶20天，尽管维生素D供应充足，但仍导致体重增加延迟和佝偻病症状。血清中钙、磷水平降低，碱性磷酸酶活性增强，骨组织矿化受到抑制，维生素D依赖性钙结合蛋白水平降低，锶在各种组织中蓄积。在鸡的日粮中添加钙可减轻上述锶中毒症状。提示钙在慢性锶中毒中的保护作用可能是由于在这些阳离子的肠道吸收过程中，对锶与钙的区分更具活性。