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男性与女性静脉吸毒者感染艾滋病毒的风险行为比较。

A comparison of male and female intravenous drug users' risk behaviors for HIV infection.

作者信息

Freeman R C, Rodriguez G M, French J F

机构信息

Data Analysis and Epidemiology Unit, Division of Alcoholism, Drug Abuse, and Addiction Services, New Jersey State Department of Health, Newark.

出版信息

Am J Drug Alcohol Abuse. 1994;20(2):129-57. doi: 10.3109/00952999409106779.

Abstract

Despite the central role played by female intravenous drug users (IVDUs) in the worsening AIDS statistics of states in the northeastern United States, the relative paucity of research into the HIV risk behaviors--particularly risky needle practices--of female drug injections has left significant gaps in researchers' understanding of how and to what extent such women may differ in their risks from their better-studied male counterparts. This study, derived from a sample of 769 out-of-treatment IVDUs residing in an area (Paterson, New Jersey) characterized by high levels of AIDS and HIV infection among drug users, attempts to address this lacuna in the research literature by comparing the drug usage, AIDS knowledge, and needle and sexual behaviors of male and female IVDUs that place them at risk for HIV infection. In this sample, gender was found to be unrelated to HIV serostatus, injection frequency and injected drug of choice, and to most dimensions of knowledge about AIDS and the means of HIV transmission. Overall, it appears that the average Paterson female IVDU may be at greater risk for HIV infection as a result of involvement with a drug-using sex partner than because of especially risky needle practices, for females in this sample were significantly more likely than males to report injecting with a sex partner in the previous 6 months, and female IVDUs with one sex partner were more than twice as likely as males with one partner to report that this individual was an IVDU. Condom use was relatively rare, particularly among those with one partner. Moreover, female IVDUs were significantly more likely than males to be daily users of crack cocaine, and significantly more likely to report poorer health. However, current needle and sexual practices were found to be unrelated to HIV seropositivity among both males and females. In logistic regression analysis, only length of IV drug involvement was found to be independently associated with HIV seropositivity for both sexes. Implications of the data for future prevention efforts aimed at female IVDUs are discussed.

摘要

尽管在美国东北部各州艾滋病统计数据恶化的情况中,女性静脉注射吸毒者(IVDUs)起到了核心作用,但针对女性吸毒者的艾滋病毒风险行为——尤其是危险的用针习惯——的研究相对较少,这使得研究人员在了解这些女性与研究较多的男性在风险方面的差异方式及程度上存在重大空白。本研究以居住在一个地区(新泽西州帕特森)的769名戒毒期IVDUs为样本,该地区吸毒者中艾滋病和艾滋病毒感染率很高,旨在通过比较男性和女性IVDUs的吸毒情况、艾滋病知识以及使其面临艾滋病毒感染风险的用针和性行为,来填补研究文献中的这一空白。在这个样本中,发现性别与艾滋病毒血清状态、注射频率和首选注射毒品无关,也与艾滋病知识及艾滋病毒传播途径的大多数方面无关。总体而言,帕特森的普通女性IVDUs似乎因与吸毒的性伴侣有接触而感染艾滋病毒的风险更大,而非因为特别危险的用针习惯,因为该样本中的女性比男性更有可能在前6个月内报告与性伴侣一起注射,且有一个性伴侣的女性IVDUs报告该伴侣为IVDUs的可能性是有一个伴侣的男性的两倍多。避孕套的使用相对较少,尤其是在只有一个伴侣的人群中。此外,女性IVDUs比男性更有可能每天吸食快克可卡因,且更有可能报告健康状况较差。然而,目前的用针和性行为被发现与男性和女性的艾滋病毒血清阳性无关。在逻辑回归分析中,仅发现静脉吸毒时间长短与男女双方的艾滋病毒血清阳性独立相关。讨论了这些数据对未来针对女性IVDUs的预防工作的启示。

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