Lasser A, Carter D M, Mahoney M J
Arch Pathol. 1975 Mar;99(3):173-6.
Skin biopsy specimens of two siblings with Hunter syndrome and two siblings with type B Sanfilippo syndrome were examined by electron microscopy, at six-month intervals, before and after plasma infusion therapy. Electron-lucent, membrane-bound vacuoles were seen in fibroblasts, Schwann cells, and in mononuclear cells both before and after the infusions. Based on the ultrastructural, clinical, and biochemical findings, it was concluded that there was no therapeutic benefit from these plasma infusions.
对两名患有亨特综合征的兄弟姐妹以及两名患有B型桑菲利普综合征的兄弟姐妹的皮肤活检标本，在血浆输注治疗前后每隔六个月进行一次电子显微镜检查。在输注前后，在成纤维细胞、施万细胞和单核细胞中均可见电子透明的膜结合空泡。根据超微结构、临床和生化检查结果，得出结论：这些血浆输注没有治疗益处。
