[糖皮质激素与急性白血病骨髓淋巴母细胞受体的相互作用]
[Interaction of glucocorticoids with bone marrow lymphoblast receptors in acute leukemia].
作者信息
Dukhanin A S, Erina T A, Bulaeva N N, Chernov V M, Stankevich L I, Kondratchik K L, Lobanovskiĭ A L
出版信息
Biull Eksp Biol Med. 1993 Feb;115(2):164-5.
PMID:8043796
Abstract
Two types of receptor systems for glucocorticoids: membranous and intracellular have been found on lymphoblasts of children with acute lymphoblastic leukemia by means of radioassay. They differed by localization and affinity for different glucocorticoids either. Modern radioassay needs modification because of no attention paying for interaction of hormones with different types of receptor system.
摘要
通过放射分析在急性淋巴细胞白血病患儿的淋巴母细胞上发现了两种糖皮质激素受体系统
膜性受体系统和细胞内受体系统。它们在定位以及对不同糖皮质激素的亲和力方面也存在差异。由于未关注激素与不同类型受体系统的相互作用，现代放射分析需要改进。
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