Dubovsky S L
Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262.
Bull Menninger Clin. 1994 Spring;58(2):197-214.
Psychotic mood disorders represent a complex group of syndromes in which depression and/or mania are accompanied by delusions, hallucinations, or both. The presence of psychotic features has a profound influence on the course and treatment response of mood disorders, and psychotic disorders in turn are influenced by coexisting dysregulation of mood. Psychosis and mood, along with other features such as severity, a high rate of recurrence, psychomotor changes, dissociation, and mental states reflecting a history of trauma, appear to interact to alter each other's expression. The treatment of psychotic mood disorders, regardless of coexisting conditions, requires pharmacotherapy--usually a combination of an antipsychotic drug and a medication for mood--or electroconvulsive therapy. The results of treatment are usually positive.
精神病性心境障碍是一组复杂的综合征，其中抑郁和/或躁狂伴有妄想、幻觉或两者皆有。精神病性特征的存在对心境障碍的病程和治疗反应有深远影响，而精神病性障碍反过来又受到并存的情绪调节异常的影响。精神病与心境，连同其他特征，如严重程度、高复发率、精神运动性改变、解离以及反映创伤史的精神状态，似乎相互作用以改变彼此的表现。无论是否存在并存情况，精神病性心境障碍的治疗都需要药物治疗——通常是抗精神病药物和心境药物的联合使用——或电休克治疗。治疗结果通常是积极的。
