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术前红细胞单采能否避免同种输血?

[Does preoperative erythroapheresis avoid homologous transfusion?].

作者信息

Beaumont J L

机构信息

Centre d'Hémobiologie-Transfusion, Groupe Hospitalier Pitié-Salpêtrière, Paris.

出版信息

Transfus Clin Biol. 1994;1(3):209-13. doi: 10.1016/s1246-7820(05)80030-8.

DOI:10.1016/s1246-7820(05)80030-8
PMID:8044317
Abstract

The risk of transfusion-related viral infections promotes techniques intended to reduce such a risk. Preoperative erythroapheresis is an autologous blood collection technique which minimizes the inconvenience of repeated predeposit autologous donations. Erythroapheresis has been performed in 451 patients, 24 to 72 hours before surgery using a discontinuous flow cell separator (PCS+Haemonetics). The mean collected red cells volume was 485 ml (250-900) and was replaced by hydroxy-ethyl-starch (ELOHES). Homologous blood transfusion was avoided in 431 patients (95,6%). This technique is indicated for surgery with an expected blood loss between 1000 and 1500 ml or when the patient cannot be included in a preoperative blood donation programme. Preoperative erythrocytapheresis is a simple and well tolerated procedure. To have recourse to apheresis techniques allows to increase the number of autologous transfused patients.

摘要

输血相关病毒感染的风险推动了旨在降低此类风险的技术发展。术前红细胞单采术是一种自体采血技术,可将重复预存式自体献血的不便降至最低。使用间断流动血细胞分离机(PCS+Haemonetics)在451例患者手术前24至72小时进行了红细胞单采术。采集的红细胞平均体积为485毫升(250-900),并用羟乙基淀粉(ELOHES)进行替代。431例患者(95.6%)避免了异体输血。该技术适用于预计失血量在1000至1500毫升之间的手术,或患者无法纳入术前献血计划的情况。术前红细胞单采术是一种简单且耐受性良好的操作。采用单采技术可以增加自体输血患者的数量。

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