Bourgoignie K, De Laey J J
Department of Ophthalmology, University Hospital, Gent, Belgium.
Bull Soc Belge Ophtalmol. 1993;248:37-45.
In a retrospective study we examined the files of 47 patients with choroidal metastasis (56 eyes of 18 male and of 29 female patients, ranging from 29 to 85 years of age). Primary breast carcinoma is the tumour most frequently responsible for choroidal metastasis (55% of the cases). Lung cancer (13% of the cases) is the most common primary tumour in males. No primary site was found in 10% of the cases. The period between the diagnosis of the primary tumour and the onset of choroidal metastasis is clearly shorter in lung cancer than in breast cancer. Furthermore, in the latter, generalized metastasis is often already known. Choroidal metastasis develops preferentially in the posterior pole. There is no preponderance of left-side involvement. It mostly concerns a solitary tumour, although multiple foci, in one or both eyes, are found in 21% of the patients. Fluoroangiography shows different patterns, but this method is not specific enough to allow differentiation from other choroidal tumours. Diagnosis is mainly supported by history, clinical context and echography.
在一项回顾性研究中，我们检查了47例脉络膜转移患者的病历（18例男性和29例女性患者的56只眼，年龄在29至85岁之间）。原发性乳腺癌是脉络膜转移最常见的肿瘤（占病例的55%）。肺癌（占病例的13%）是男性最常见的原发性肿瘤。10%的病例未发现原发部位。肺癌患者从原发性肿瘤诊断到脉络膜转移发生的时间明显短于乳腺癌患者。此外，在乳腺癌患者中，通常已经出现全身转移。脉络膜转移优先发生于后极部。左侧受累并无优势。大多数情况下为孤立性肿瘤，不过21%的患者在一只或两只眼睛中发现有多个病灶。荧光血管造影显示出不同的模式，但该方法特异性不足，无法与其他脉络膜肿瘤相鉴别。诊断主要依靠病史、临床背景和超声检查。
