Zheng X G, Zhang T H, Lu Z F
Department of Ultrastructural Pathology, Jinling Hospital, Nanjing.
Zhonghua Bing Li Xue Za Zhi. 1994 Feb;23(1):26-8.
Right ventricle myocardium of 25 cases of tetralogy of Fallot and 11 cases of ventricle septal defect were studied by both light and electron microscopy. Normal human myocardium from 4 cases were used as the control. The resulting data indicate that the mean muscle diameter correlated significantly with the course of disease, mean pressure of right ventricle and diameter of ventricle septal defect. In 6 cases with congenital heart disease, the myocardium was atrophic and presented with 2 types of ultrastructural features: accumulation of Z-line material or hyperplasia of the mitochondria. The significance of these ultrastructural findings in congenital heart disease is discussed.
对25例法洛四联症和11例室间隔缺损患者的右心室心肌进行了光镜和电镜研究。以4例正常人的心肌作为对照。结果数据表明，平均肌纤维直径与病程、右心室平均压力及室间隔缺损直径显著相关。6例先天性心脏病患者的心肌萎缩，并呈现出两种超微结构特征：Z线物质积聚或线粒体增生。文中讨论了这些先天性心脏病超微结构发现的意义。
