Shi Z J
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1994;12(1):1-6.
Twenty-one villages from ten provinces and one autonomous region with different mf rates in population and different levels of mean mf density per 60 microliters blood in positive cases and representative species of filaria and vector after DEC treatment were selected as study sites. In these villages a longitudinal investigation for a period of 3-5 years was carried out without adopting any control measure. The main results were: 1. Among 279 residual microfilaremia cases, 235 (84.2%) turned negative spontaneously and successively. The negative conversion rates were 86.6% (46/53) in malayan cases, 60.8% (28/46) in bancroftian cases after 3 years' follow-up, and 100% (29/29) in malayan cases, 87.4% (132/151) in bancroftian cases after 4-5 year's follow-up. Among 110 bancroftian cases followed-up to seven years, 109 (99.1%) turned negative. 2. Twenty-two new microfilaremia cases were detected, of which, 18 might be missed in previous blood examination, 4 might be new infection. 3. Mf rate in the population in twenty villages has been trending down, whereas in one village fluctuated around the original level. Among the 20 villages, no microfilaremia case was found in 7 villages. 4. The natural infection rates of filarial larvae and infective rates in mosquito vectors were in descending trend in most of these villages, and no filarial larva was found in 12 villages.(ABSTRACT TRUNCATED AT 250 WORDS)
从10个省和1个自治区中选取了21个村庄作为研究地点，这些村庄人口中的微丝蚴率不同，阳性病例每60微升血液中的平均微丝蚴密度水平不同，丝虫种类和乙胺嗪治疗后的媒介具有代表性。在这些村庄中，未采取任何控制措施，进行了为期3至5年的纵向调查。主要结果如下：1. 在279例残留微丝蚴血症病例中，235例（84.2%）先后自然转阴。马来丝虫病病例3年随访后的转阴率为86.6%（46/53），班氏丝虫病病例为60.8%（28/46）；4至5年随访后，马来丝虫病病例转阴率为100%（29/29），班氏丝虫病病例为87.4%（132/151）。在随访至7年的110例班氏丝虫病病例中，109例（99.1%）转阴。2. 检测到22例新的微丝蚴血症病例，其中18例可能是之前血液检查漏检的，4例可能是新感染病例。3. 20个村庄的人群微丝蚴率呈下降趋势，而1个村庄在原水平附近波动。在这20个村庄中，7个村庄未发现微丝蚴血症病例。4. 大多数村庄的丝虫幼虫自然感染率和蚊媒感染率呈下降趋势，12个村庄未发现丝虫幼虫。（摘要截短于250字）
