Nilsson S E, Montan P G
Department of Ophthalmology, University of Linköping, Sweden.
CLAO J. 1994 Apr;20(2):97-101.
All hospitalized cases of contact lens induced keratitis with stromal involvement among cosmetic wearers in Sweden over a 3-year period were reviewed for risk factors in relation to lens type and wear schedule. Information on every case was obtained from ophthalmology departments. Lens type and wear schedule were identified. The number of lens wearers, subdivided by lens type and wear schedule, was obtained from a study by the Swedish Contact Lens Association. Annual incidence figures were then calculated as expressions of risk factors. There were 30.7 cases per year, on average, of hospitalized lens induced keratitis in Sweden. The annual incidence per 10,000 wearers was 0.51 for daily wear and 3.12 for extended wear of conventional soft lenses, 0.16 for daily wear and 4.17 for extended wear of disposable soft lenses, and 1.21 for daily wear of rigid gas permeable lenses. It may be concluded that daily wear of disposable lenses was associated with significantly (P < 0.05-0.01) less risk of hospitalized keratitis than daily wear of the other lens types. Extended wear of conventional and disposable soft lenses showed a significantly (P < 0.01-0.001) higher risk of hospitalized keratitis than daily wear. However, the two extended wear groups did not differ significantly (P > 0.2). Microbial keratitis was significantly (P < 0.001) more common than sterile (no growth of microbes) keratitis among conventional soft lens wearers, whereas the opposite was true (P < 0.05) among disposable lens wearers.
对瑞典3年间所有因佩戴隐形眼镜导致角膜基质受累的住院病例进行回顾,以分析与镜片类型和佩戴时间相关的危险因素。每个病例的信息均来自眼科科室。确定了镜片类型和佩戴时间。镜片佩戴者的数量按镜片类型和佩戴时间细分,数据来自瑞典隐形眼镜协会的一项研究。然后计算年发病率以作为危险因素的指标。瑞典每年平均有30.7例因佩戴隐形眼镜导致角膜基质受累的住院病例。每10000名佩戴者中,传统软性隐形眼镜日戴的年发病率为0.51,长戴的年发病率为3.12;一次性软性隐形眼镜日戴的年发病率为0.16,长戴的年发病率为4.17;硬性透气性隐形眼镜日戴的年发病率为1.21。可以得出结论,与其他类型镜片的日戴相比,一次性镜片日戴导致住院性角膜炎的风险显著降低(P < 0.05 - 0.01)。传统软性隐形眼镜和一次性软性隐形眼镜长戴导致住院性角膜炎的风险显著高于日戴(P < 0.01 - 0.001)。然而,两个长戴组之间没有显著差异(P > 0.2)。在传统软性隐形眼镜佩戴者中,微生物性角膜炎显著(P < 0.001)比无菌性(无微生物生长)角膜炎更常见,而在一次性隐形眼镜佩戴者中情况则相反(P < 0.05)。