Santucci M, Burg G, Feller A C
Institute of Anatomic Pathology, University of Florence Medical School, Italy.
Dermatol Clin. 1994 Apr;12(2):323-7.
Researchers in many fields have become increasingly aware of the observer as an important source of measurement error. Consequently, reliability studies must be conducted in experimental or survey situations to assess the level of observer variability in the measurement procedures to be used in data acquisition. The present investigation demonstrated that interobserver and intraobserver variability is generally high, even between investigators internationally recognized for their experience in lymphomatous disorders and even when dealing with noninitial CTCL lesions. Similarly, sensitivity and specificity are generally low, the former astonishingly, without significant differences between early and noninitial CTCL lesions.
许多领域的研究人员越来越意识到观察者是测量误差的一个重要来源。因此，必须在实验或调查环境中进行可靠性研究，以评估在数据采集过程中所使用的测量程序中观察者变异的程度。本研究表明，即使在国际上以淋巴瘤疾病经验著称的研究人员之间，甚至在处理非初发性蕈样肉芽肿（CTCL）病变时，观察者间和观察者内的变异通常也很高。同样，敏感性和特异性通常较低，令人惊讶的是，早期和非初发性CTCL病变之间没有显著差异。
