用于检测A群链球菌的快速检测方法的评估

Evaluation of a rapid test to detect Streptococcus group A.

作者信息

Amir J, Rotman M, Schwartz K, Maayan R, Varsano I

机构信息

Department of Pediatrics C, Children's Medical Center of Israel, Petah, Tikva.

出版信息

Isr J Med Sci. 1994 Aug;30(8):617-9.

PMID:8045743

Abstract

Rapid tests for the detection of group A beta-hemolytic streptococcus (GABHS) directly from a throat swab have become very popular. Previous studies have reported an antigen test sensitivity of 55-95% and a specificity of 88-100%. The present study evaluates the reliability of one rapid test in detecting GABHS (PathoDx). A total of 164 throat swab specimens was taken. GABHS was isolated on the culture in 37 (22.5%), and the rapid test was positive in 60 (36.6%). The sensitivity of the rapid test was 86.5% and the specificity 80%. Of the 60 positive rapid test results, 28 (47%) were false positive and the positive predicted value was 53%. We conclude that results obtained using rapid test kits should be compared to throat cultures in order to determine the reliability of such kits in specific clinical settings.

摘要

直接从咽拭子检测A组β溶血性链球菌（GABHS）的快速检测方法已非常普遍。以往研究报告抗原检测敏感性为55%-95%，特异性为88%-100%。本研究评估了一种检测GABHS的快速检测方法（PathoDx）的可靠性。共采集了164份咽拭子标本。37份（22.5%）标本经培养分离出GABHS，快速检测60份（36.6%）呈阳性。快速检测的敏感性为86.5%，特异性为80%。在60份快速检测阳性结果中，28份（47%）为假阳性，阳性预测值为53%。我们得出结论，使用快速检测试剂盒获得的结果应与咽拭子培养结果进行比较，以确定此类试剂盒在特定临床环境中的可靠性。