Gainer J L
Department of Chemical Engineering, University of Virginia, Charlottesville 22903-2442.
J Appl Physiol (1985). 1994 Apr;76(4):1826-9. doi: 10.1152/jappl.1994.76.4.1826.
A series of studies over the past several years has been concerned with O2 consumption in the gastrocnemius muscle of the dog. Those experiments indicate that the maximal O2 consumption may be diffusion limited and suggest that such data can be correlated using a parameter, the O2 diffusing capacity, that combines different effects. An analysis of those data is presented here with use of multiple linear regression techniques, which indicate that, even if the experimental conditions are different, the diffusing capacity can be quantitatively evaluated if the blood flow rate, hemoglobin content, and blood pressure are known. Although the data are for a specific tissue, similar results might be expected when O2 consumption is considered in other tissues.
在过去几年里，一系列研究聚焦于犬腓肠肌的氧气消耗。这些实验表明，最大氧气消耗可能受扩散限制，并表明这些数据可以通过一个参数——氧气扩散能力来关联，该参数综合了不同的影响。本文运用多元线性回归技术对这些数据进行了分析，结果表明，即使实验条件不同，但如果已知血流速率、血红蛋白含量和血压，就可以对扩散能力进行定量评估。尽管这些数据是针对特定组织的，但在考虑其他组织的氧气消耗时，可能会得到类似的结果。
