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药物引起的皮肤血管型过敏反应(作者译)

[Drug-induced allergic skin reactions of a cutaneous vascular type (author's transl)].

作者信息

Pevny I, Röckl H

出版信息

MMW Munch Med Wochenschr. 1975 Jan 3;117(1):9-16.

PMID:804598
Abstract

Among drug exanthemata (AE) are included allergic reactions of the cutaneous system which are of a cutaneous vascular type after hematogenous supply of the allergen, which run an immunological course according to the early, Arthus or late type. They are manifested morphologically as urticaria (monosymptomatic or a partial symptom of an anaphylactic or serum sickness syndrome), as macular or maculopapular exanthema (9 days AE) predominantly after ampicillin, as a fixed AE, as Lyell's disease (fatal in about 30% of cases), as erythema multiforme-like AE, as purpura (allergic vasculitis, "carbromal purpura"), as rare lichenoides or nodose AE and as erythematodes-like drug reactions.

摘要

药疹(AE)包括皮肤系统的过敏反应,这些反应是在变应原经血流供应后出现的皮肤血管型反应,根据早期、Arthus型或晚期类型呈免疫性病程。其形态学表现为荨麻疹(单症状或过敏性或血清病综合征的部分症状)、斑疹或斑丘疹性皮疹(9日疹型AE),主要在使用氨苄西林后出现、固定性药疹、Lyell病(约30%的病例可致死)、多形红斑样药疹、紫癜(过敏性血管炎,“卡溴脲紫癜”)、罕见的苔藓样或结节样药疹以及红斑样药物反应。

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