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非甾体抗炎药。当前的眼科治疗方法。

Nonsteroidal anti-inflammatory drugs. Current ophthalmic therapy.

作者信息

Abelson M B, Sloan J

机构信息

Department of Ophthalmology, Harvard Medical School, Boston, MS.

出版信息

J Fla Med Assoc. 1994 Apr;81(4):261-3.

PMID:8046366
Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of ophthalmic inflammatory disease. Currently four topical preparations are available: flurbiprofen and suprofen for the prevention of miosis during surgery; diclofenac for postoperative inflammation following cataract extraction, and ketorolac for the treatment of itching associated with seasonal allergic conjunctivitis. Caution should be exercised, however, as topical and systemic adverse effects may occur including stinging, photophobia, gastric sensitivity, and increased bleeding time. The mechanism of action of NSAIDs is discussed, complications associated with use, and the current and future roles of therapy.

摘要

非甾体抗炎药(NSAIDs)常用于治疗眼部炎性疾病。目前有四种局部用制剂:氟比洛芬和舒洛芬用于预防手术期间的瞳孔缩小;双氯芬酸用于白内障摘除术后的炎症,酮咯酸用于治疗与季节性过敏性结膜炎相关的瘙痒。然而,应谨慎使用,因为可能会出现局部和全身不良反应,包括刺痛、畏光、胃部敏感和出血时间延长。本文讨论了NSAIDs的作用机制、使用相关的并发症以及当前和未来的治疗作用。

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Nonsteroidal anti-inflammatory drugs. Current ophthalmic therapy.非甾体抗炎药。当前的眼科治疗方法。
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Nonsteroidal anti-inflammatory drugs in ophthalmology.眼科中的非甾体类抗炎药。
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Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation.0.1%双氯芬酸和0.5%酮咯酸眼用溶液治疗后后囊膜混浊的发生率:3年随机、双盲、前瞻性临床研究。
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