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Cymbion疗效与耐受性对照试验(作者译)

[Controlled trial of Cymbi on efficacy and tolerance (author's transl)].

作者信息

Bräuer H, Villanyi P, Votin J

出版信息

MMW Munch Med Wochenschr. 1975 Feb 28;117(9):353-6.

PMID:804644
Abstract

Ampicillin (Cymbi -Dolorgiet) was administered in various administration forms to 139 patients with acute and chronic infections of the urinary tract, biliary tract and other infections for an average of 10 days under conditions similar to those of general practice. In a controlled investigation the efficacy and tolerance were examined, and in parallel studies the in vitro activities were correlated with the blood levels obtainable in vivo to determine the therapeutic value in the treated group. The chemotherapeutic efficacy was high and the tolerance was good. The incidence of side effects was relatively low. Only 3;5% of the patients showed unfavorable results or had to stop the treatment.

摘要

氨苄西林(凯米必妥)以多种剂型给药,在与一般临床情况相似的条件下,对139例患有急慢性泌尿道感染、胆道感染及其他感染的患者进行了平均为期10天的治疗。在一项对照研究中,对其疗效和耐受性进行了检测,同时在平行研究中,将体外活性与体内可达到的血药浓度相关联,以确定治疗组的治疗价值。化疗效果良好,耐受性也佳。副作用发生率相对较低。只有3.5%的患者出现不良结果或不得不停止治疗。

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