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钇-90治疗应用中的轫致辐射剂量

Bremsstrahlung radiation dose in yttrium-90 therapy applications.

作者信息

Stabin M G, Eckerman K F, Ryman J C, Williams L E

机构信息

Radiation Internal Dose Information Center, Oak Ridge Institute for Science and Education, TN 37831-0117.

出版信息

J Nucl Med. 1994 Aug;35(8):1377-80.

PMID:8046497
Abstract

UNLABELLED

The bremsstrahlung component of the decay scheme of beta emitters has been traditionally ignored in internal dosimetry calculations.

METHODS

We have estimated the radiation dose from the bremsstrahlung component of the decay scheme of 90Y as a function of distance from a point source in a liquid medium and to body organs from distributed sources of 90Y in the liver and spleen.

RESULTS

These estimates agree with measurements of bremsstrahlung dose measured in a Rando phantom, and give an estimate of the importance of this contribution to the overall dosimetry.

CONCLUSIONS

The bremsstrahlung radiation absorbed dose contribution from an organ to itself is very small compared to that from the beta dose, but the contribution to other organs is not always negligible, especially when large amounts of 90Y may be involved, as in therapy applications.

摘要

未标注

在内部剂量学计算中,传统上一直忽略β发射体衰变图中的轫致辐射成分。

方法

我们估算了90Y衰变图中轫致辐射成分产生的辐射剂量,该剂量是液体介质中距点源距离的函数,也是肝脏和脾脏中90Y分布源对身体器官产生剂量的函数。

结果

这些估算值与在兰多人体模型中测量的轫致辐射剂量相符,并给出了这一成分对总体剂量学贡献重要性的估算。

结论

与β剂量相比,器官自身的轫致辐射吸收剂量贡献非常小,但对其他器官的贡献并非总是可以忽略不计,特别是在治疗应用中可能涉及大量90Y的情况下。

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