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[感染对儿童癫痫治疗过程及疗效的影响]

[Effect of infections on the course and effectiveness of epilepsy treatment in children].

作者信息

Kazibutowska Z, Filipowicz A, Kudybka E

出版信息

Neurol Neurochir Pol. 1975 Jan-Feb;9(1):65-71.

PMID:804669
Abstract

The analysis was carried out in a group of 32 children with coexistent chronic urinary tract or respiratory infections. In 20 children an unfavourable effect of infection on the course of epilepsy was observed. Worsening of epilepsy during infection was observed mainly in children without evidence of nervous system damage with primarily generalized seizures, and in cases when the first attacks developed after protective vaccinations. The effect of urinary tract infections was particularly unfavourable. The authors put forward the hypothesis of immunological basis of exacerbation of epileptic seizures during chronic infections.

摘要

该分析是在一组32名同时患有慢性尿路感染或呼吸道感染的儿童中进行的。在20名儿童中观察到感染对癫痫病程有不利影响。感染期间癫痫恶化主要见于无神经系统损害证据、以全身强直发作为主的儿童,以及首次发作在预防性接种疫苗后出现的病例。尿路感染的影响尤为不利。作者提出了慢性感染期间癫痫发作加重的免疫学基础假说。

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