Takami K, Suzuki M, Horiuchi T
Kanto Central Hospital.
Nihon Rinsho. 1994 Jun;52(6):1599-602.
Sarcoidosis is a multisystem granulomatous disorder of unknown etiology presenting with bilateral hilar lymphadenopathy, pulmonary, skin, and eye lesion. Sarcoidosis involving skeletal muscle is not uncommon because non caseating granuloma have been demonstrated in as much as 50 to 80% of sarcoidosis cases. Symptomatic muscle involvement, however, is rare. Chronic and acute myopathy and palpable nodular lesions due to sarcoidosis involving skeletal muscle have been reported. Chronic myopathy is progressive muscle disease with muscle weakness and wasting. Because this syndrome is rare, its natural history and responsiveness to corticosteroid have not been defined well. We review the medical literature of previously reported cases of muscular sarcoidosis.
结节病是一种病因不明的多系统肉芽肿性疾病,表现为双侧肺门淋巴结肿大、肺部、皮肤和眼部病变。结节病累及骨骼肌并不罕见,因为在多达50%至80%的结节病病例中已证实存在非干酪样肉芽肿。然而,有症状的肌肉受累情况很少见。已有关于结节病累及骨骼肌导致慢性和急性肌病以及可触及的结节性病变的报道。慢性肌病是一种进行性肌肉疾病,伴有肌肉无力和萎缩。由于这种综合征很少见,其自然病程和对皮质类固醇的反应尚未明确界定。我们回顾了先前报道的肌肉结节病病例的医学文献。