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[终末期慢性肾功能不全患者当前治疗的某些方面]

[Some aspects of current treatment of patients with terminal chronic renal insufficiency].

作者信息

Burtsev V I, Grankin V I, Briukhovetskiĭ A G, Klopotskiĭ S A, Miasnikova E B

出版信息

Klin Med (Mosk). 1993 Jan;71(1):33-6.

PMID:8046902
Abstract

Two groups of patients with terminal chronic renal failure (TCRF) treated from 1970 to 1979 (group 1) and in 1980-1989 (group 2) have been compared in respect to treatment results. All the patients underwent programmed hemodialysis performed on different equipment and according to different regimens. The results of group 2 appeared better: the lethality decreased by 18%, mean survival from 6 months to 4.5 years, up to half of the patients were able to receive hemodialysis procedures outpatiently, 30% of the patients were prepared to receive a renal transplant. The above positive shifts were achieved due to utilization of updated equipment, improved water purification, 3-stage technique of hemodialysis, antianemic drug eprex and vanalpha against osteodystrophy.

摘要

对1970年至1979年(第1组)以及1980年至1989年(第2组)接受治疗的两组终末期慢性肾衰竭(TCRF)患者的治疗结果进行了比较。所有患者均按照不同方案在不同设备上进行了计划性血液透析。第2组的结果更好:死亡率降低了18%,平均生存期从6个月延长至4.5年,多达一半的患者能够在门诊接受血液透析治疗,30%的患者准备接受肾移植。上述积极变化得益于采用了更新的设备、改进了水净化、采用了三阶段血液透析技术、使用了抗贫血药物依泊汀以及使用了防治骨营养不良的药物万阿法。

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