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[肿瘤性和血管性脑疾病的临床多态性:发病机制特点]

[Clinical polymorphism of neoplastic and vascular brain diseases: pathogenetic characteristics].

作者信息

Shmyrev V I

出版信息

Klin Med (Mosk). 1993;71(2):17-21.

PMID:8046915
Abstract

Using evidence on 533 patients with an atypical course of brain tumors and vascular diseases, the author discusses the role of the vascular factor in polymorphism of clinical manifestations of tumors and metastases to the brain. It is shown that in 55.4% of cases brain tumors simulated CNS affections. Of these most frequent was the picture of cerebral circulatory disturbances. Mechanisms causing cerebral circulation impairment in various tumors and metastases to the brain are considered. It is found that pathologically changed circulation and angioarchitecture of the tumors may contribute to a wide spectrum of clinical signs typical for vascular brain diseases. The conclusions are based on the analysis of the results obtained with present-day techniques of angio- and neurovisualization and postoperative as well as autopsy examinations of the tumors.

摘要

作者利用533例脑肿瘤和血管疾病非典型病程患者的证据,探讨了血管因素在肿瘤临床表现多态性及脑转移中的作用。结果显示,55.4%的脑肿瘤病例表现类似中枢神经系统疾病。其中最常见的是脑循环障碍表现。文中探讨了各种脑肿瘤和转移瘤导致脑循环障碍的机制。研究发现,肿瘤病理改变的循环和血管结构可能导致一系列典型的脑血管疾病临床症状。这些结论基于对当前血管造影和神经影像学技术所得结果以及肿瘤术后和尸检检查结果的分析。

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