McKearney J W, Barrett J E
Psychopharmacologia. 1975;41(1):23-6. doi: 10.1007/BF00421301.
Responding maintained in squirrel monkeys under a 10-min fixed-interval schedule of food presentation was suppressed by presenting a shock after every 30th response (punishment). During alternate 10-min periods of the same experimental session, but in the presence of a different discriminative stimulus, responding either had no effect (extinction) or postponed delivery of an electric shock (avoidance). During sessions when the avoidance schedule was not in effect, d-amphetamine sulfate decreased punished responding. When the avoidance schedule was present during alternate 10-min periods, however, d-amphetamine (0.01 minus 0.56 mg/kg, i.m.) markedly increased responding during punishment components. Increases in responding during avoidance components were also evident. The effects of d-amphetamine on punished responding depend on the context in which that responding occurs.
在每30次反应后给予电击（惩罚）的情况下，松鼠猴在10分钟固定间隔食物呈现时间表下的反应受到抑制。在同一实验时段的交替10分钟期间，但在不同的辨别性刺激存在时，反应要么没有影响（消退），要么推迟电击的施加（回避）。在回避时间表无效的时段，硫酸右苯丙胺减少了受惩罚的反应。然而，当在交替的10分钟期间存在回避时间表时，右苯丙胺（0.01至0.56毫克/千克，肌肉注射）在惩罚成分期间显著增加了反应。在回避成分期间反应的增加也很明显。右苯丙胺对受惩罚反应的影响取决于该反应发生的背景。
