Rossi A, Zalaffi A, Decchi B
Laboratorio di Neurofisiologia dell'Istituto di Scienze Neurologiche, Toro, Italy.
Neurosci Lett. 1994 Mar 14;169(1-2):141-4. doi: 10.1016/0304-3940(94)90376-x.
Presence of heteronymous recurrent inhibition in motoneurones (Mns) innervating the soleus muscle (Sol) was investigated following electrical stimulation of the nerve of gastrocnemius medialis muscle (GM). Sub-threshold electrical stimulation for alpha Mns produced short-lasting inhibition of the Sol, reflecting non-reciprocal group I inhibition. After increasing the intensity of stimulation above the motor threshold, a short-latency, long-lasting inhibition appeared superimposed on the group I inhibition. Its amount increased with the size of the conditioning motor response and after acute administration of L-acetylcarnitine. It is concluded that this long-lasting inhibition of the Sol Mns is due to the heteronymous activity of the GM-coupled Renshaw cells.
