Mglinets V A
Ontogenez. 1994 May-Jun;25(3):66-73.
The comparative dermatoglyphic analysis of palms and fingers of seven children with different forms of macrodactyly showed that they are fairly similar to those of normal children. The differences concern certain flattening of papillary ridges and reduced parameters of the total ridge count in the patients. Only in two cases of macrodactyly an increase in the relative length of fingers was accompanied by an increase in number of epidermal ridges and in the distance between fingers. If macrodactyly is based on somatic mutations or recombinations, then, depending on the time when the resulting mutant cell clones appear (before or after the epidermal ridges are laid down), the increased size of finger rudiments will or will not affect the value of ridge count.
对七名患有不同类型巨指症的儿童的手掌和手指进行的比较皮纹分析表明,他们与正常儿童的皮纹相当相似。差异在于患者的乳头嵴有一定程度的扁平以及总嵴数参数降低。仅在两例巨指症病例中,手指相对长度的增加伴随着表皮嵴数量的增加以及手指间距离的增加。如果巨指症是基于体细胞突变或重组,那么,根据产生的突变细胞克隆出现的时间(在表皮嵴形成之前或之后),手指原基增大的尺寸将会或不会影响嵴数的值。