Krensky A M, Clayberger C
Department of Pediatrics, Stanford University School of Medicine, California.
Pediatr Clin North Am. 1994 Aug;41(4):819-39. doi: 10.1016/s0031-3955(16)38809-5.
A major function of the immune response is the discrimination of self from nonself. It is this response that must be overcome in transplant rejection. Progress in understanding these basic immune mechanisms has helped to improve clinical outcome and lays the foundation for a new generation of therapies.