Pilz P
Virchows Arch A Pathol Anat Histol. 1975;366(1):59-66. doi: 10.1007/BF00438678.
The origin of hemolytic anemia, the histogenesis of vascular changes and the origin of prethrombotic lesion are discussed in a typical case of thrombotic thrombocytopenic purpura (TTP) with early neurological symptoms. The disease arose after exposure to a chloronaphtalene containing substance. In addition to the typical vascular changes of different age, early non-endothelialised and non obstructing aggregates of fibrin and thrombocytes are observed. Clusters of drop-like deformed erythrocytes and elongated leucocytes are attached to their surface. These changes do not appear to have been reported previously in TTP. The fresh thrombi are regarded as being hematologically active. Support for their supposed causal relationship to hemolytic anemia is given by experimental data by Brain and Bull.
在一例伴有早期神经症状的血栓性血小板减少性紫癜（TTP）典型病例中，探讨了溶血性贫血的起源、血管变化的组织发生以及血栓前病变的起源。该疾病在接触含氯萘的物质后出现。除了不同时期典型的血管变化外，还观察到早期未内皮化且未阻塞的纤维蛋白和血小板聚集体。水滴状变形红细胞和拉长的白细胞簇附着在它们的表面。这些变化似乎以前在TTP中未曾报道过。新鲜血栓被认为具有血液学活性。Brain和Bull的实验数据支持了它们与溶血性贫血假定的因果关系。
