Galler J R, Tonkiss J, Maldonado-Irizarry C S
Center for Behavioral Development and Mental Retardation, Boston University School of Medicine, MA 02118.
Physiol Behav. 1994 Jun;55(6):993-6. doi: 10.1016/0031-9384(94)90379-4.
Home orienting behavior was studied during the first 11 days of life in prenatally protein-malnourished and well-nourished rat pups, both groups having been reared by well-nourished mothers since birth. On all days of testing, mean weights were compromised in the prenatally malnourished pups relative to their well-nourished age controls (body weight deficit = 19-29%). Eye opening was also significantly delayed in the malnourished group. On the test of homing behavior, malnourished pups were significantly impaired in their ability to locate the nest on days 9 and 11. The effect was not related to activity levels of the pups, which were generally similar in the two nutritional groups. Thus, prenatal malnutrition disturbs the development of the homing response in the early postnatal period.
在出生后的前11天，对出生前蛋白质营养不良和营养良好的幼鼠的归巢行为进行了研究，自出生以来，两组幼鼠均由营养良好的母鼠抚养。在所有测试日，相对于营养良好的同龄对照幼鼠，出生前营养不良的幼鼠平均体重受到影响（体重不足19%-29%）。营养不良组的睁眼时间也明显延迟。在归巢行为测试中，营养不良的幼鼠在第9天和第11天定位巢穴的能力明显受损。这种影响与幼鼠的活动水平无关，两个营养组的幼鼠活动水平通常相似。因此，产前营养不良会干扰出生后早期归巢反应的发育。
