[The periodontal reaction to root canal obturation with different filling materials].

Periodontal reactions and the apexification process in the teeth with open apex of the root in response to different filling materials and the relationship between these processes and the quality of filling of the root channels were studied in experiments. Zinc-eugenol paste, intradont, itradont-D and intradont with lysozyme were used to fill the root channels in puppies aged 6-7 months. Filling of the root channel up to the apex was found to be the optimal variant, preventing the development of necrosis and promoting periodontal tissue regeneration.