Rudaia N V, Syvachenko O E, Alferov A N, Bychkar' E M, Korzhov V I
Ukr Biokhim Zh (1978). 1993 Nov-Dec;65(6):108-11.
Quantity and activity of components in the monoxygenase system of the liver microsomes have been studied for their dependence on the phenotype of acetylation. Results of investigations are presented. The majority of these enzymes exist as numerous molecular forms: isozymes. It is shown that activity of aminopyrine-N-demethylase and NADPH-cytochrome P-450 reductase depends on the phenotype of acetyltransferase.
已研究了肝微粒体单加氧酶系统中各组分的数量和活性对乙酰化表型的依赖性。现将研究结果呈现如下。这些酶中的大多数以多种分子形式存在:同工酶。结果表明,氨基比林 - N - 脱甲基酶和NADPH - 细胞色素P - 450还原酶的活性取决于乙酰转移酶的表型。